| 세션명 | 대학원생 구두발표 (I) |
|---|---|
| 발표장 | 제10회장 |
| 논문코드 | O10-5 |
| 발표일 | 2024-04-3 |
| 발표시간 | 14:00-14:15 |
| 논문제목 | Engineering Superhydrophilic Gel-Like Coatings for Antifouling and Antithrombotic Surface Modification via Layer-by-Layer Assembly |
| 발표자 | 장세윤 |
| 발표자 소속 | 한국과학기술연구원 |
| 저자 | 장세윤, 권일근1, 정영미, 류진† |
| 소속 | 한국과학기술연구원; 1경희대학교 |
| 논문초록 | When medical devices come into contact with blood, they undergo non-specific protein adhesion and denaturation, which can lead to thrombosis, inflammation, and device failure. We developed a biocompatible, superhydrophilic antifouling and antithrombotic gel-like coating to mitigate these issues. This coating is engineered through layer-by-layer assembly of poly-L-lysine, laponite (disc-shaped clay particles), and heparin, utilizing eletrostatic interactions. The inner layer forms a gel-like structure with laponite, maintaining superhydrophilicity to prevent protein and cell adhesion. Meanwhile, the outer heparin layer acts to prevent blood clot formation by inhibiting plasma protein adsorption and platelet activation. This coating retains its superhydrophilic properties and heparin stability after immersion in PBS for seven days, demonstrating its potential applicability across various implantable medical devices. |
THE POLYMER SOCIETY OF KOREA